PDB 5kzi

PDB Information

PDB5KZI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors.
Wurz, R.P., Sastri, C., D'Amico, D.C., Herberich, B., Jackson, C.L., Pettus, L.H., Tasker, A.S., Wu, B., Guerrero, N., Lipford, J.R., Winston, J.T., Yang, Y., Wang, P., Nguyen, Y., Andrews, K.L., Huang, X., Lee, M.R., Mohr, C., Zhang, J.D., Reid, D.L., Xu, Y., Zhou, Y., Wang, H.L.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Inhibitor
Released2016-07-25
Resolution2.100
CATH Insert Date20 Nov, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5kziA01 24 Nov, 2016 3.30.200.20 Assigned
5kziA02 24 Nov, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1