PDB 5kyj

PDB Links
Overview

PDB Information

PDB	5KYJ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core. Tice, C.M., Noto, P.B., Fan, K.Y., Zhao, W., Lotesta, S.D., Dong, C., Marcus, A.P., Zheng, Y.J., Chen, G., Wu, Z., Van Orden, R., Zhou, J., Bukhtiyarov, Y., Zhao, Y., Lipinski, K., Howard, L., Guo, J., Kandpal, G., Meng, S., Hardy, A., Krosky, P., Gregg, R.E., Leftheris, K., McKeever, B.M., Singh, S.B., Lala, D., McGeehan, G.M., Zhuang, L., Claremon, D.A. Bioorg.Med.Chem.Lett.
Header	Dna Binding Protein
Released	2016-07-21
Resolution	2.800
CATH Insert Date	09 Oct, 2016

PDB Images (9)

Image of CATH 5kyj

5kyj

PDB 5kyj

Image of CATH 5kyjA

5kyjA

PDB Chain 5kyjA

Image of CATH 5kyjB

5kyjB

PDB Chain 5kyjB

Image of CATH 5kyjE

5kyjE

PDB Chain 5kyjE

Image of CATH 5kyjF

5kyjF

PDB Chain 5kyjF

Image of CATH 5kyjA00

5kyjA00

CATH Domain 5kyjA00

Image of CATH 5kyjB00

5kyjB00

CATH Domain 5kyjB00

Image of CATH 5kyjE00

5kyjE00

CATH Domain 5kyjE00

Image of CATH 5kyjF00

5kyjF00

CATH Domain 5kyjF00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	10 Oct, 2016	Chopped
B	10 Oct, 2016	Chopped
E	10 Oct, 2016	Chopped
F	10 Oct, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5kyjA00	30 Nov, 2016	1.10.565.10	Assigned
5kyjB00	03 Jul, 2018	1.10.565.10	Assigned
5kyjE00	30 Nov, 2016	1.10.565.10	Assigned
5kyjF00	03 Jul, 2018	1.10.565.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28702	RXRB_HUMAN	Homo sapiens	Retinoic acid receptor RXR-beta
P28702	RXRB_HUMAN	Homo sapiens	Retinoic acid receptor RXR-beta
P55055	NR1H2_HUMAN	Homo sapiens	Oxysterols receptor LXR-beta
P55055	NR1H2_HUMAN	Homo sapiens	Oxysterols receptor LXR-beta