PDB 5kx8

PDB Information

PDB5KX8
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Efforts towards the optimization of a bi-aryl class of potent IRAK4 inhibitors.
Hanisak, J., Seganish, W.M., McElroy, W.T., Tang, H., Zhang, R., Tsui, H.C., Fischmann, T., Tulshian, D., Tata, J., Sondey, C., Devito, K., Fossetta, J., Garlisi, C.G., Lundell, D., Niu, X.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2016-07-20
Resolution2.670
CATH Insert Date04 Sep, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2016 Chopped
B 05 Sep, 2016 Chopped
C 05 Sep, 2016 Chopped
D 05 Sep, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5kx8A01 09 Sep, 2016 3.30.200.20 Assigned
5kx8A02 09 Sep, 2016 1.10.510.10 Assigned
5kx8B01 12 Jul, 2018 Check for files
5kx8B02 12 Jul, 2018 Check for files
5kx8C01 12 Jul, 2018 Check for files
5kx8C02 12 Jul, 2018 Check for files
5kx8D01 08 Sep, 2016 3.30.200.20 Assigned
5kx8D02 08 Sep, 2016 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4