PDB 5kx5

PDB Information

PDB5KX5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads.
Leverett, C.A., Sukuru, S.C., Vetelino, B.C., Musto, S., Parris, K., Pandit, J., Loganzo, F., Varghese, A.H., Bai, G., Liu, B., Liu, D., Hudson, S., Doppalapudi, V.R., Stock, J., O'Donnell, C.J., Subramanyam, C.
ACS Med Chem Lett
HeaderStructural Protein/Inhibitor
Released2016-07-20
Resolution2.500
CATH Insert Date08 Jan, 2017

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 09 Jan, 2017 Chopped
B 09 Jan, 2017 Chopped
C 09 Jan, 2017 Chopped
D 09 Jan, 2017 Chopped
E 09 Jan, 2017 Chopped
F 09 Jan, 2017 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5kx5A01 19 Jan, 2017 3.40.50.1440 Assigned
5kx5A02 19 Jan, 2017 3.30.1330.20 Assigned
5kx5A03 19 Jan, 2017 1.10.287.600 Assigned
5kx5B01 19 Jan, 2017 3.40.50.1440 Assigned
5kx5B02 19 Jan, 2017 3.30.1330.20 Assigned
5kx5B03 19 Jan, 2017 1.10.287.600 Assigned
5kx5C01 19 Jan, 2017 3.40.50.1440 Assigned
5kx5C02 19 Jan, 2017 3.30.1330.20 Assigned
5kx5C03 19 Jan, 2017 1.10.287.600 Assigned
5kx5D01 19 Jan, 2017 3.40.50.1440 Assigned
5kx5D02 19 Jan, 2017 3.30.1330.20 Assigned
5kx5D03 19 Jan, 2017 1.10.287.600 Assigned
5kx5E01 19 Jan, 2017 6.10.280.30 Assigned
5kx5F01 19 Jan, 2017 3.40.50.11480 Assigned
5kx5F02 19 Jan, 2017 3.30.470.20 Assigned
5kx5F03 19 Jan, 2017 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
D0VWZ0 D0VWZ0_SHEEP Ovis aries Tubulin alpha chain
D0VWY9 D0VWY9_SHEEP Ovis aries Tubulin beta chain
D0VWY9 D0VWY9_SHEEP Ovis aries Tubulin beta chain
D0VWZ0 D0VWZ0_SHEEP Ovis aries Tubulin alpha chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
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