PDB Information

PDB5KCW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Srinivasan, S., Nwachukwu, J.C., Bruno, N.E., Dharmarajan, V., Goswami, D., Kastrati, I., Novick, S., Nowak, J., Cavett, V., Zhou, H.B., Boonmuen, N., Zhao, Y., Min, J., Frasor, J., Katzenellenbogen, B.S., Griffin, P.R., Katzenellenbogen, J.A., Nettles, K.W.
Nat. Chem. Biol.
HeaderTranscription
Released2016-06-07
Resolution1.910
CATH Insert Date27 Nov, 2016

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Nov, 2016 Chopped
B 28 Nov, 2016 Chopped
C 28 Nov, 2016 Rejected
D 28 Nov, 2016 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5kcwA00 02 Dec, 2016 1.10.565.10 Assigned
5kcwB00 02 Dec, 2016 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor