PDB 5k4l

PDB Links
Overview

PDB Information

PDB	5K4L
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors. Labadie, S.S., Dragovich, P.S., Cummings, R.T., Deshmukh, G., Gustafson, A., Han, N., Harmange, J.C., Kiefer, J.R., Li, Y., Liang, J., Liederer, B.M., Liu, Y., Manieri, W., Mao, W., Murray, L., Ortwine, D.F., Trojer, P., VanderPorten, E., Vinogradova, M., Wen, L. Bioorg.Med.Chem.Lett.
Header	Oxidoreductase/Inhibitor
Released	2016-05-20
Resolution	3.180
CATH Insert Date	04 Sep, 2016

PDB Images (11)

Image of CATH 5k4l

5k4l

PDB 5k4l

Image of CATH 5k4lA

5k4lA

PDB Chain 5k4lA

Image of CATH 5k4lB

5k4lB

PDB Chain 5k4lB

Image of CATH 5k4lF

5k4lF

PDB Chain 5k4lF

Image of CATH 5k4lG

5k4lG

PDB Chain 5k4lG

Image of CATH 5k4lA01

5k4lA01

CATH Domain 5k4lA01

Image of CATH 5k4lA02

5k4lA02

CATH Domain 5k4lA02

Image of CATH 5k4lA03

5k4lA03

CATH Domain 5k4lA03

Image of CATH 5k4lB01

5k4lB01

CATH Domain 5k4lB01

Image of CATH 5k4lB02

5k4lB02

CATH Domain 5k4lB02

Image of CATH 5k4lB03

5k4lB03

CATH Domain 5k4lB03

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	05 Sep, 2016	Chopped
B	05 Sep, 2016	Chopped
F	05 Sep, 2016	Rejected
G	05 Sep, 2016	Rejected

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5k4lA01	16 Feb, 2017	2.60.120.650	Assigned
5k4lA02	16 Feb, 2017	1.10.150.60	Assigned
5k4lA03	16 Feb, 2017		Holding pen
5k4lB01	16 Feb, 2017	2.60.120.650	Assigned
5k4lB02	16 Feb, 2017	1.10.150.60	Assigned
5k4lB03	16 Feb, 2017		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P29375	KDM5A_HUMAN	Homo sapiens	Lysine-specific demethylase 5A
P29375	KDM5A_HUMAN	Homo sapiens	Lysine-specific demethylase 5A