PDB 5k0b

PDB Information

PDB5K0B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceRattus norvegicus
Primary Citation
Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O-Methyltransferase Derived from a Fragment Screening Approach Targeting the S-Adenosyl-l-methionine Pocket.
Lerner, C., Jakob-Roetne, R., Buettelmann, B., Ehler, A., Rudolph, M., Rodriguez Sarmiento, R.M.
J. Med. Chem.
HeaderTransferase
Released2016-05-17
Resolution2.360
CATH Insert Date16 Oct, 2016

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped
E 17 Oct, 2016 Chopped
F 17 Oct, 2016 Chopped
G 17 Oct, 2016 Chopped
H 17 Oct, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5k0bA01 22 Oct, 2016 3.40.50.150 Assigned
5k0bB01 22 Oct, 2016 3.40.50.150 Assigned
5k0bC01 22 Oct, 2016 3.40.50.150 Assigned
5k0bD01 22 Oct, 2016 3.40.50.150 Assigned
5k0bE01 21 Oct, 2016 3.40.50.150 Assigned
5k0bF01 22 Oct, 2016 3.40.50.150 Assigned
5k0bG01 22 Oct, 2016 3.40.50.150 Assigned
5k0bH01 22 Oct, 2016 3.40.50.150 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase