PDB 5jlj

PDB Links
Overview

PDB Information

PDB	5JLJ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies. Hing, Z.A., Fung, H.Y., Ranganathan, P., Mitchell, S., El-Gamal, D., Woyach, J.A., Williams, K., Goettl, V.M., Smith, J., Yu, X., Meng, X., Sun, Q., Cagatay, T., Lehman, A.M., Lucas, D.M., Baloglu, E., Shacham, S., Kauffman, M.G., Byrd, J.C., Chook, Y.M., Garzon, R., Lapalombella, R. Leukemia
Header	Protein Transport
Released	2016-04-27
Resolution	2.500
CATH Insert Date	10 Jul, 2016

PDB Images (7)

Image of CATH 5jlj

5jlj

PDB 5jlj

Image of CATH 5jljA

5jljA

PDB Chain 5jljA

Image of CATH 5jljB

5jljB

PDB Chain 5jljB

Image of CATH 5jljC

5jljC

PDB Chain 5jljC

Image of CATH 5jljA00

5jljA00

CATH Domain 5jljA00

Image of CATH 5jljB00

5jljB00

CATH Domain 5jljB00

Image of CATH 5jljC00

5jljC00

CATH Domain 5jljC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	11 Jul, 2016	Chopped
B	11 Jul, 2016	Chopped
C	11 Jul, 2016	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5jljA00	20 Jul, 2016	3.40.50.300	Assigned
5jljB00	20 Jul, 2016	2.30.29.30	Assigned
5jljC00	16 Feb, 2017		Holding pen

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P62826	RAN_HUMAN	Homo sapiens	GTP-binding nuclear protein Ran
P30822	XPO1_YEAST	Saccharomyces cerevisiae S288C	Exportin-1
P41920	YRB1_YEAST	Saccharomyces cerevisiae S288C	Ran-specific GTPase-activating protein 1