PDB Information

PDB5J7F
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
1,4,5-Trisubstituted Imidazole-Based p53-MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers.
Twarda-Clapa, A., Krzanik, S., Kubica, K., Guzik, K., Labuzek, B., Neochoritis, C.G., Khoury, K., Kowalska, K., Czub, M., Dubin, G., Domling, A., Skalniak, L., Holak, T.A.
J. Med. Chem.
HeaderLigase
Released2016-04-06
Resolution2.000
CATH Insert Date21 May, 2017

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 22 May, 2017 Chopped
B 22 May, 2017 Chopped
C 22 May, 2017 Chopped
D 22 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5j7fA00 06 Nov, 2017 1.10.245.10 Assigned
5j7fB00 06 Nov, 2017 1.10.245.10 Assigned
5j7fC00 06 Nov, 2017 1.10.245.10 Assigned
5j7fD00 06 Nov, 2017 1.10.245.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2