PDB 5ipj

PDB Information

PDB5IPJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors.
Pettus, L.H., Andrews, K.L., Booker, S.K., Chen, J., Cee, V.J., Chavez, F., Chen, Y., Eastwood, H., Guerrero, N., Herberich, B., Hickman, D., Lanman, B.A., Laszlo, J., Lee, M.R., Lipford, J.R., Mattson, B., Mohr, C., Nguyen, Y., Norman, M.H., Powers, D., Reed, A.B., Rex, K., Sastri, C., Tamayo, N., Wang, P., Winston, J.T., Wu, B., Wu, T., Wurz, R.P., Xu, Y., Zhou, Y., Tasker, A.S., Wang, H.L.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-03-09
Resolution2.100
CATH Insert Date10 Jul, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Jul, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ipjA01 18 Jul, 2016 3.30.200.20 Assigned
5ipjA02 18 Jul, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1