PDB 5iis

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Overview

PDB Information

PDB	5IIS
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold. Nishiguchi, G.A., Burger, M.T., Han, W., Lan, J., Atallah, G., Tamez, V., Lindvall, M., Bellamacina, C., Garcia, P., Feucht, P., Zavorotinskaya, T., Dai, Y., Wong, K. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2016-03-01
Resolution	2.100
CATH Insert Date	17 Apr, 2016

PDB Images (4)

Image of CATH 5iis

5iis

PDB 5iis

Image of CATH 5iisA

5iisA

PDB Chain 5iisA

Image of CATH 5iisA01

5iisA01

CATH Domain 5iisA01

Image of CATH 5iisA02

5iisA02

CATH Domain 5iisA02

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	18 Apr, 2016	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5iisA01	15 May, 2016	3.30.200.20	Assigned
5iisA02	15 May, 2016	1.10.510.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P11309	PIM1_HUMAN	Homo sapiens	Serine/threonine-protein kinase pim-1