PDB 5if1

PDB Information

PDB5IF1
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9.
Ayaz, P., Andres, D., Kwiatkowski, D.A., Kolbe, C.C., Lienau, P., Siemeister, G., Lucking, U., Stegmann, C.M.
Acs Chem.Biol.
HeaderTransferase
Released2016-02-25
Resolution2.610
CATH Insert Date08 May, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 09 May, 2016 Chopped
B 09 May, 2016 Chopped
C 09 May, 2016 Chopped
D 09 May, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5if1A01 18 Jul, 2016 3.30.200.20 Assigned
5if1A02 18 Jul, 2016 1.10.510.10 Assigned
5if1B01 17 Jul, 2016 1.10.472.10 Assigned
5if1B02 17 Jul, 2016 1.10.472.10 Assigned
5if1C01 18 Jul, 2016 3.30.200.20 Assigned
5if1C02 18 Jul, 2016 1.10.510.10 Assigned
5if1D01 18 Jul, 2016 1.10.472.10 Assigned
5if1D02 18 Jul, 2016 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2