PDB 5i2k

PDB Information

PDB5I2K
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.
Volgraf, M., Sellers, B.D., Jiang, Y., Wu, G., Ly, C.Q., Villemure, E., Pastor, R.M., Yuen, P.W., Lu, A., Luo, X., Liu, M., Zhang, S., Sun, L., Fu, Y., Lupardus, P.J., Wallweber, H.J., Liederer, B.M., Deshmukh, G., Plise, E., Tay, S., Reynen, P., Herrington, J., Gustafson, A., Liu, Y., Dirksen, A., Dietz, M.G., Liu, Y., Wang, T.M., Hanson, J.E., Hackos, D., Scearce-Levie, K., Schwarz, J.B.
J.Med.Chem.
HeaderTransport Protein
Released2016-02-09
Resolution2.860
CATH Insert Date10 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5i2kA01 15 May, 2016 3.40.190.10 Assigned
5i2kA02 15 May, 2016 3.40.190.10 Assigned
5i2kB01 15 May, 2016 3.40.190.10 Assigned
5i2kB02 15 May, 2016 3.40.190.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q12879 NMDE1_HUMAN Homo sapiens Glutamate receptor ionotropic, NMDA 2A
Q05586 NMDZ1_HUMAN Homo sapiens Glutamate receptor ionotropic, NMDA 1