PDB 5hyn

PDB Links
Overview

PDB Information

PDB	5HYN
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2. Justin, N., Zhang, Y., Tarricone, C., Martin, S.R., Chen, S., Underwood, E., De Marco, V., Haire, L.F., Walker, P.A., Reinberg, D., Wilson, J.R., Gamblin, S.J. Nat Commun
Header	Transferase
Released	2016-02-01
Resolution	2.950
CATH Insert Date	29 May, 2016

PDB Images (29)

5hyn

PDB 5hyn

5hynA

PDB Chain 5hynA

5hynB

PDB Chain 5hynB

5hynC

PDB Chain 5hynC

5hynD

PDB Chain 5hynD

5hynE

PDB Chain 5hynE

5hynF

PDB Chain 5hynF

5hynG

PDB Chain 5hynG

5hynH

PDB Chain 5hynH

5hynI

PDB Chain 5hynI

5hynJ

PDB Chain 5hynJ

5hynK

PDB Chain 5hynK

5hynL

PDB Chain 5hynL

5hynM

PDB Chain 5hynM

5hynO

PDB Chain 5hynO

5hynP

PDB Chain 5hynP

5hynQ

PDB Chain 5hynQ

5hynR

PDB Chain 5hynR

5hynS

PDB Chain 5hynS

5hynT

PDB Chain 5hynT

5hynU

PDB Chain 5hynU

5hynB00

CATH Domain 5hynB00

5hynC01

CATH Domain 5hynC01

5hynG00

CATH Domain 5hynG00

5hynH01

CATH Domain 5hynH01

5hynL00

CATH Domain 5hynL00

5hynM01

CATH Domain 5hynM01

5hynR00

CATH Domain 5hynR00

5hynS01

CATH Domain 5hynS01

PDB Prints

PDB Chains (20)

Chain ID	Date inserted into CATH	CATH Status
A	30 May, 2016	Holding pen
B	30 May, 2016	Chopped
C	30 May, 2016	Chopped
D	30 May, 2016	Rejected
E	30 May, 2016	Rejected
F	30 May, 2016	Domchop review
G	30 May, 2016	Chopped
H	30 May, 2016	Chopped
I	30 May, 2016	Rejected
J	30 May, 2016	Rejected
K	30 May, 2016	Holding pen
L	30 May, 2016	Chopped
M	30 May, 2016	Chopped
O	30 May, 2016	Rejected
P	30 May, 2016	Rejected
Q	30 May, 2016	Holding pen
R	30 May, 2016	Chopped
S	30 May, 2016	Chopped
T	30 May, 2016	Rejected
U	30 May, 2016	Rejected

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5hynB00	17 Jul, 2016	2.130.10.10	Assigned
5hynC01	11 Jan, 2018		Holding pen
5hynG00	17 Jul, 2016	2.130.10.10	Assigned
5hynH01	11 Jan, 2018		Holding pen
5hynL00	17 Jul, 2016	2.130.10.10	Assigned
5hynM01	11 Jan, 2018		Write scan list
5hynR00	17 Jul, 2016	2.130.10.10	Assigned
5hynS01	11 Jan, 2018		Holding pen

UniProtKB Entries (16)

Accession	Gene ID	Taxon	Description
Q15910	EZH2_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase EZH2
Q15910	EZH2_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase EZH2
P68431	H31_HUMAN	Homo sapiens	Histone H3.1
O75530	EED_HUMAN	Homo sapiens	Polycomb protein EED
Q15910	EZH2_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase EZH2
P68431	H31_HUMAN	Homo sapiens	Histone H3.1
Q92833	JARD2_HUMAN	Homo sapiens	Protein Jumonji
O75530	EED_HUMAN	Homo sapiens	Polycomb protein EED
O75530	EED_HUMAN	Homo sapiens	Polycomb protein EED
Q15910	EZH2_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase EZH2
P68431	H31_HUMAN	Homo sapiens	Histone H3.1
P68431	H31_HUMAN	Homo sapiens	Histone H3.1
Q92833	JARD2_HUMAN	Homo sapiens	Protein Jumonji
Q92833	JARD2_HUMAN	Homo sapiens	Protein Jumonji
O75530	EED_HUMAN	Homo sapiens	Polycomb protein EED
Q92833	JARD2_HUMAN	Homo sapiens	Protein Jumonji