PDB 5h74

PDB Information

PDB5H74
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Structure-Activity Relationship Studies of Tubulysin Analogues: Anticancer N-Alkyltubulysins with Subpicomolar Activity and the Crystal Structure Binding to Tubulin
Wang, Y., Yu, Y., Chen, Q., Yang, J.
To Be Published
HeaderStructural Protein/Inhibitor
Released2016-11-17
Resolution2.600
CATH Insert Date17 Dec, 2017

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped
B 17 Dec, 2017 Chopped
C 17 Dec, 2017 Chopped
D 17 Dec, 2017 Chopped
E 17 Dec, 2017 Chopped
F 17 Dec, 2017 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5h74A01 21 Dec, 2017 3.40.50.1440 Assigned
5h74A02 21 Dec, 2017 3.30.1330.20 Assigned
5h74A03 21 Dec, 2017 1.10.287.600 Assigned
5h74B01 21 Dec, 2017 3.40.50.1440 Assigned
5h74B02 21 Dec, 2017 3.30.1330.20 Assigned
5h74B03 21 Dec, 2017 1.10.287.600 Assigned
5h74C01 21 Dec, 2017 3.40.50.1440 Assigned
5h74C02 21 Dec, 2017 3.30.1330.20 Assigned
5h74C03 21 Dec, 2017 1.10.287.600 Assigned
5h74D01 21 Dec, 2017 3.40.50.1440 Assigned
5h74D02 21 Dec, 2017 3.30.1330.20 Assigned
5h74D03 21 Dec, 2017 1.10.287.600 Assigned
5h74E01 21 Dec, 2017 6.10.280.30 Assigned
5h74F01 21 Dec, 2017 3.40.50.11480 Assigned
5h74F02 21 Dec, 2017 3.30.470.20 Assigned
5h74F03 21 Dec, 2017 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain