PDB 5f91

PDB Information

PDB5F91
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Primary Citation
Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.
Kasbekar, M., Fischer, G., Mott, B.T., Yasgar, A., Hyvonen, M., Boshoff, H.I., Abell, C., Barry, C.E., Thomas, C.J.
Proc.Natl.Acad.Sci.USA
HeaderLyase/Lyase Inhibitor
Released2015-12-09
Resolution2.000
CATH Insert Date17 Jul, 2016

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 18 Jul, 2016 Chopped
B 18 Jul, 2016 Chopped
C 18 Jul, 2016 Chopped
D 18 Jul, 2016 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5f91A01 01 Sep, 2016 1.10.275.10 Assigned
5f91A02 01 Sep, 2016 1.20.200.10 Assigned
5f91A03 01 Sep, 2016 1.10.40.30 Assigned
5f91B01 01 Sep, 2016 1.10.275.10 Assigned
5f91B02 01 Sep, 2016 1.20.200.10 Assigned
5f91B03 01 Sep, 2016 1.10.40.30 Assigned
5f91C01 01 Sep, 2016 1.10.275.10 Assigned
5f91C02 01 Sep, 2016 1.20.200.10 Assigned
5f91C03 01 Sep, 2016 1.10.40.30 Assigned
5f91D01 01 Sep, 2016 1.10.275.10 Assigned
5f91D02 01 Sep, 2016 1.20.200.10 Assigned
5f91D03 01 Sep, 2016 1.10.40.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P9WN92 FUMC_MYCTO Mycobacterium tuberculosis CDC1551 Fumarate hydratase class II
P9WN92 FUMC_MYCTO Mycobacterium tuberculosis CDC1551 Fumarate hydratase class II
P9WN92 FUMC_MYCTO Mycobacterium tuberculosis CDC1551 Fumarate hydratase class II
P9WN92 FUMC_MYCTO Mycobacterium tuberculosis CDC1551 Fumarate hydratase class II