PDB 5exl

PDB Information

PDB5EXL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group
Corte, J.R., Fang, T., Pinto, D.J.P., Orwat, M.J., Han, W., Rendina, A.R., Luettgen, J.M., Rossi, K.A., Wei, A., Ramamurthy, V., Myers Jr., J.E., Sheriff, S., Narayanan, R., Harper, T., Zheng, J.J., Li, Y.-X., Seiffert, D.A., Wexler, R.R., Quan, M.L.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-11-23
Resolution2.300
CATH Insert Date24 Apr, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5exlA01 09 May, 2016 2.40.10.10 Assigned
5exlA02 09 May, 2016 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI
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