PDB Information

PDB5ETL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli
Primary Citation
Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli.
Dennis, M.L., Pitcher, N.P., Lee, M.D., DeBono, A.J., Wang, Z.C., Harjani, J.R., Rahmani, R., Cleary, B., Peat, T.S., Baell, J.B., Swarbrick, J.D.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2015-11-17
Resolution1.820
CATH Insert Date15 May, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped
B 16 May, 2016 Chopped
C 16 May, 2016 Chopped
D 16 May, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5etlA00 15 Jul, 2016 3.30.70.560 Assigned
5etlB00 15 Jul, 2016 3.30.70.560 Assigned
5etlC00 15 Jul, 2016 3.30.70.560 Assigned
5etlD00 15 Jul, 2016 3.30.70.560 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P26281 HPPK_ECOLI Escherichia coli K-12 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
P26281 HPPK_ECOLI Escherichia coli K-12 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
P26281 HPPK_ECOLI Escherichia coli K-12 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
P26281 HPPK_ECOLI Escherichia coli K-12 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase