PDB 5en5

PDB Information

PDB5EN5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli (strain K12)
Primary Citation
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Sjuts, H., Vargiu, A.V., Kwasny, S.M., Nguyen, S.T., Kim, H.S., Ding, X., Ornik, A.R., Ruggerone, P., Bowlin, T.L., Nikaido, H., Pos, K.M., Opperman, T.J.
Proc.Natl.Acad.Sci.USA
HeaderTransport Protein
Released2015-11-09
Resolution2.300
CATH Insert Date17 Apr, 2016

PDB Images (25)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2016 Chopped
B 18 Apr, 2016 Chopped
C 18 Apr, 2016 Chopped
D 18 Apr, 2016 Chopped
E 18 Apr, 2016 Chopped
F 18 Apr, 2016 Chopped

CATH Domains (18)

Domain ID Date inserted into CATH Superfamily CATH Status
5en5A01 09 Jan, 2018 3.30.70.1430 Assigned
5en5A02 09 Jan, 2018 3.30.70.1320 Assigned
5en5A03 09 Jan, 2018 Holding pen
5en5A04 09 Jan, 2018 3.30.70.1430 Assigned
5en5A05 09 Jan, 2018 3.30.70.1440 Assigned
5en5B01 09 Jan, 2018 3.30.70.1430 Assigned
5en5B02 09 Jan, 2018 3.30.70.1320 Assigned
5en5B03 09 Jan, 2018 Holding pen
5en5B04 09 Jan, 2018 3.30.70.1430 Assigned
5en5B05 09 Jan, 2018 3.30.70.1440 Assigned
5en5C01 09 Jan, 2018 3.30.70.1430 Assigned
5en5C02 09 Jan, 2018 3.30.70.1320 Assigned
5en5C03 09 Jan, 2018 Holding pen
5en5C04 09 Jan, 2018 3.30.70.1430 Assigned
5en5C05 09 Jan, 2018 3.30.70.1440 Assigned
5en5D00 30 Nov, 2016 1.25.40.20 Assigned
5en5E00 30 Nov, 2016 1.25.40.20 Assigned
5en5F00 30 Nov, 2016 1.25.40.20 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P31224 ACRB_ECOLI Escherichia coli K-12 Multidrug efflux pump subunit AcrB
P31224 ACRB_ECOLI Escherichia coli K-12 Multidrug efflux pump subunit AcrB
P31224 ACRB_ECOLI Escherichia coli K-12 Multidrug efflux pump subunit AcrB