PDB Information

PDB5EEQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Gunzburg, M.J., Kulkarni, K., Watson, G.M., Ambaye, N.D., Del Borgo, M.P., Brandt, R., Pero, S.C., Perlmutter, P., Wilce, M.C., Wilce, J.A.
Sci Rep
HeaderSignaling Protein/Inhibitor
Released2015-10-23
Resolution1.600
CATH Insert Date10 Jul, 2016

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 11 Jul, 2016 Chopped
B 11 Jul, 2016 Chopped
L 11 Jul, 2016 Rejected
M 11 Jul, 2016 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5eeqA00 14 Jul, 2016 3.30.505.10 Assigned
5eeqB00 14 Jul, 2016 3.30.505.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7