PDB 5eel

PDB Information

PDB5EEL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Gunzburg, M.J., Kulkarni, K., Watson, G.M., Ambaye, N.D., Del Borgo, M.P., Brandt, R., Pero, S.C., Perlmutter, P., Wilce, M.C., Wilce, J.A.
Sci Rep
HeaderSignaling Protein/Peptide
Released2015-10-23
Resolution2.470
CATH Insert Date10 Jul, 2016

PDB Images (19)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 11 Jul, 2016 Chopped
B 11 Jul, 2016 Chopped
C 11 Jul, 2016 Chopped
D 11 Jul, 2016 Chopped
E 11 Jul, 2016 Chopped
F 11 Jul, 2016 Chopped
L 11 Jul, 2016 Rejected
M 11 Jul, 2016 Rejected
N 11 Jul, 2016 Rejected
P 11 Jul, 2016 Rejected
Q 11 Jul, 2016 Rejected
R 11 Jul, 2016 Rejected

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5eelA00 14 Jul, 2016 3.30.505.10 Assigned
5eelB00 14 Jul, 2016 3.30.505.10 Assigned
5eelC00 14 Jul, 2016 3.30.505.10 Assigned
5eelD00 14 Jul, 2016 3.30.505.10 Assigned
5eelE00 14 Jul, 2016 3.30.505.10 Assigned
5eelF00 14 Jul, 2016 3.30.505.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7