PDB 5eds

PDB Links
Overview

PDB Information

PDB	5EDS
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3K delta Inhibitors. Shin, Y., Suchomel, J., Cardozo, M., Duquette, J., He, X., Henne, K., Hu, Y.L., Kelly, R.C., McCarter, J., McGee, L.R., Medina, J.C., Metz, D., San Miguel, T., Mohn, D., Tran, T., Vissinga, C., Wong, S., Wannberg, S., Whittington, D.A., Whoriskey, J., Yu, G., Zalameda, L., Zhang, X., Cushing, T.D. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2015-10-21
Resolution	2.800
CATH Insert Date	10 Jan, 2016

PDB Images (7)

Image of CATH 5eds

5eds

PDB 5eds

Image of CATH 5edsA

5edsA

PDB Chain 5edsA

Image of CATH 5edsA01

5edsA01

CATH Domain 5edsA01

Image of CATH 5edsA02

5edsA02

CATH Domain 5edsA02

Image of CATH 5edsA03

5edsA03

CATH Domain 5edsA03

Image of CATH 5edsA04

5edsA04

CATH Domain 5edsA04

Image of CATH 5edsA05

5edsA05

CATH Domain 5edsA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	11 Jan, 2016	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5edsA01	13 Jan, 2016	3.10.20.90	Assigned
5edsA02	13 Jan, 2016	2.60.40.150	Assigned
5edsA03	13 Jan, 2016	1.25.40.70	Assigned
5edsA04	13 Jan, 2016	3.30.1010.10	Assigned
5edsA05	13 Jan, 2016	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform