PDB 5edq

PDB Information

PDB5EDQ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase.
Hanan, E.J., Baumgardner, M., Bryan, M.C., Chen, Y., Eigenbrot, C., Fan, P., Gu, X.H., La, H., Malek, S., Purkey, H.E., Schaefer, G., Schmidt, S., Sideris, S., Yen, I., Yu, C., Heffron, T.P.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-10-21
Resolution2.800
CATH Insert Date20 Dec, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Dec, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5edqA01 05 Jan, 2016 3.30.200.20 Assigned
5edqA02 05 Jan, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor