PDB Information

PDB5E0K
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Primary Citation
Directed evolution of the tryptophan synthase beta-subunit for stand-alone function recapitulates allosteric activation.
Buller, A.R., Brinkmann-Chen, S., Romney, D.K., Herger, M., Murciano-Calles, J., Arnold, F.H.
Proc.Natl.Acad.Sci.USA
HeaderLyase
Released2015-09-29
Resolution2.760
CATH Insert Date29 Nov, 2015

PDB Images (31)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 30 Nov, 2015 Chopped
B 30 Nov, 2015 Chopped
C 30 Nov, 2015 Chopped
D 30 Nov, 2015 Chopped
E 30 Nov, 2015 Chopped
F 30 Nov, 2015 Chopped
G 30 Nov, 2015 Chopped
H 30 Nov, 2015 Chopped
I 30 Nov, 2015 Chopped
J 30 Nov, 2015 Chopped
K 30 Nov, 2015 Chopped
L 30 Nov, 2015 Chopped

CATH Domains (18)

Domain ID Date inserted into CATH Superfamily CATH Status
5e0kA00 03 Dec, 2015 3.20.20.70 Assigned
5e0kB01 03 Dec, 2015 3.40.50.1100 Assigned
5e0kB02 03 Dec, 2015 3.40.50.1100 Assigned
5e0kC00 02 Dec, 2015 3.20.20.70 Assigned
5e0kD01 03 Dec, 2015 3.40.50.1100 Assigned
5e0kD02 03 Dec, 2015 3.40.50.1100 Assigned
5e0kE00 03 Dec, 2015 3.20.20.70 Assigned
5e0kF01 03 Dec, 2015 3.40.50.1100 Assigned
5e0kF02 03 Dec, 2015 3.40.50.1100 Assigned
5e0kG00 03 Dec, 2015 3.20.20.70 Assigned
5e0kH01 03 Dec, 2015 3.40.50.1100 Assigned
5e0kH02 03 Dec, 2015 3.40.50.1100 Assigned
5e0kI00 03 Dec, 2015 3.20.20.70 Assigned
5e0kJ01 03 Dec, 2015 3.40.50.1100 Assigned
5e0kJ02 03 Dec, 2015 3.40.50.1100 Assigned
5e0kK00 03 Dec, 2015 3.20.20.70 Assigned
5e0kL01 03 Dec, 2015 3.40.50.1100 Assigned
5e0kL02 03 Dec, 2015 3.40.50.1100 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q8U093 TRPB1_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase beta chain 1
Q8U093 TRPB1_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase beta chain 1
Q8U093 TRPB1_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase beta chain 1
Q8U094 TRPA_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase alpha chain
Q8U094 TRPA_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase alpha chain
Q8U093 TRPB1_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase beta chain 1
Q8U094 TRPA_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase alpha chain
Q8U094 TRPA_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase alpha chain
Q8U094 TRPA_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase alpha chain
Q8U093 TRPB1_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase beta chain 1
Q8U094 TRPA_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase alpha chain
Q8U093 TRPB1_PYRFU Pyrococcus furiosus DSM 3638 Tryptophan synthase beta chain 1