PDB 5dh5

PDB Links
Overview

PDB Information

PDB	5DH5
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of pyrazolopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Raheem, I.T., Schreier, J.D., Fuerst, J., Gantert, L., Hostetler, E.D., Huszar, S., Joshi, A., Kandebo, M., Kim, S.H., Li, J., Ma, B., McGaughey, G., Sharma, S., Shipe, W.D., Uslaner, J., Vandeveer, G.H., Yan, Y., Renger, J.J., Smith, S.M., Coleman, P.J., Cox, C.D. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-08-29
Resolution	2.000
CATH Insert Date	10 Apr, 2016

PDB Images (5)

Image of CATH 5dh5

5dh5

PDB 5dh5

Image of CATH 5dh5A

5dh5A

PDB Chain 5dh5A

Image of CATH 5dh5B

5dh5B

PDB Chain 5dh5B

Image of CATH 5dh5A00

5dh5A00

CATH Domain 5dh5A00

Image of CATH 5dh5B00

5dh5B00

CATH Domain 5dh5B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5dh5A00	07 May, 2016	1.10.1300.10	Assigned
5dh5B00	07 May, 2016	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A