PDB 5dfp

PDB Information

PDB5DFP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.
Ndubaku, C.O., Crawford, J.J., Drobnick, J., Aliagas, I., Campbell, D., Dong, P., Dornan, L.M., Duron, S., Epler, J., Gazzard, L., Heise, C.E., Hoeflich, K.P., Jakubiak, D., La, H., Lee, W., Lin, B., Lyssikatos, J.P., Maksimoska, J., Marmorstein, R., Murray, L.J., O'Brien, T., Oh, A., Ramaswamy, S., Wang, W., Zhao, X., Zhong, Y., Blackwood, E., Rudolph, J.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-08-27
Resolution2.200
CATH Insert Date10 Apr, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5dfpA01 07 May, 2016 3.30.200.20 Assigned
5dfpA02 07 May, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q13153 PAK1_HUMAN Homo sapiens Serine/threonine-protein kinase PAK 1