PDB 5d3e

PDB Information

PDB5D3E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.
Stevers, L.M., Lam, C.V., Leysen, S.F., Meijer, F.A., van Scheppingen, D.S., de Vries, R.M., Carlile, G.W., Milroy, L.G., Thomas, D.Y., Brunsveld, L., Ottmann, C.
Proc.Natl.Acad.Sci.USA
HeaderSignaling Protein
Released2015-08-06
Resolution2.750
CATH Insert Date10 Apr, 2016

PDB Images (16)

PDB Prints

PDB Chains (9)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Rejected
E 11 Apr, 2016 Chopped
F 11 Apr, 2016 Chopped
G 11 Apr, 2016 Rejected
I 11 Apr, 2016 Chopped
J 11 Apr, 2016 Chopped
K 11 Apr, 2016 Rejected

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5d3eA00 06 May, 2016 1.20.190.20 Assigned
5d3eB00 06 May, 2016 1.20.190.20 Assigned
5d3eE00 06 May, 2016 1.20.190.20 Assigned
5d3eF00 06 May, 2016 1.20.190.20 Assigned
5d3eI00 06 May, 2016 1.20.190.20 Assigned
5d3eJ00 06 May, 2016 1.20.190.20 Assigned

UniProtKB Entries (9)

Accession Gene ID Taxon Description
P61981 1433G_HUMAN Homo sapiens 14-3-3 protein gamma
P13569 CFTR_HUMAN Homo sapiens Cystic fibrosis transmembrane conductance regulator
P61981 1433G_HUMAN Homo sapiens 14-3-3 protein gamma
P61981 1433G_HUMAN Homo sapiens 14-3-3 protein gamma
P61981 1433G_HUMAN Homo sapiens 14-3-3 protein gamma
P13569 CFTR_HUMAN Homo sapiens Cystic fibrosis transmembrane conductance regulator
P61981 1433G_HUMAN Homo sapiens 14-3-3 protein gamma
P13569 CFTR_HUMAN Homo sapiens Cystic fibrosis transmembrane conductance regulator
P61981 1433G_HUMAN Homo sapiens 14-3-3 protein gamma