PDB 5czb

PDB Information

PDB5CZB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus subtype 1b
Primary Citation
Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.
Pierra Rouviere, C., Amador, A., Badaroux, E., Convard, T., Da Costa, D., Dukhan, D., Griffe, L., Griffon, J.F., LaColla, M., Leroy, F., Liuzzi, M., Loi, A.G., McCarville, J., Mascia, V., Milhau, J., Onidi, L., Paparin, J.L., Rahali, R., Sais, E., Seifer, M., Surleraux, D., Standring, D., Dousson, C.
Bioorg.Med.Chem.Lett.
HeaderReplication
Released2015-07-31
Resolution1.960
CATH Insert Date10 Jul, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Jul, 2016 Chopped
B 11 Jul, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5czbA01 13 Jul, 2016 Holding pen
5czbA02 13 Jul, 2016 Holding pen
5czbB01 13 Jul, 2016 Holding pen
5czbB02 13 Jul, 2016 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein