PDB 5csw

PDB Links
Overview

PDB Information

PDB	5CSW
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation. Waizenegger, I.C., Baum, A., Steurer, S., Stadtmuller, H., Bader, G., Schaaf, O., Garin-Chesa, P., Schlattl, A., Schweifer, N., Haslinger, C., Colbatzky, F., Mousa, S., Kalkuhl, A., Kraut, N., Adolf, G.R. Mol.Cancer Ther.
Header	Transferase
Released	2015-07-23
Resolution	2.660
CATH Insert Date	10 Apr, 2016

PDB Images (7)

Image of CATH 5csw

5csw

PDB 5csw

Image of CATH 5cswA

5cswA

PDB Chain 5cswA

Image of CATH 5cswB

5cswB

PDB Chain 5cswB

Image of CATH 5cswA01

5cswA01

CATH Domain 5cswA01

Image of CATH 5cswA02

5cswA02

CATH Domain 5cswA02

Image of CATH 5cswB01

5cswB01

CATH Domain 5cswB01

Image of CATH 5cswB02

5cswB02

CATH Domain 5cswB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5cswA01	05 May, 2016	3.30.200.20	Assigned
5cswA02	05 May, 2016	1.10.510.10	Assigned
5cswB01	05 May, 2016	3.30.200.20	Assigned
5cswB02	05 May, 2016	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf