PDB 5cf4

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Overview

PDB Information

PDB	5CF4
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5-d]pyrrolo[2,3-b]pyridine Inhibitors. Hart, A.C., Schroeder, G.M., Wan, H., Grebinski, J., Inghrim, J., Kempson, J., Guo, J., Pitts, W.J., Tokarski, J.S., Sack, J.S., Khan, J.A., Lippy, J., Lorenzi, M.V., You, D., McDevitt, T., Vuppugalla, R., Zhang, Y., Lombardo, L.J., Trainor, G.L., Purandare, A.V. Acs Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2015-07-08
Resolution	2.380
CATH Insert Date	06 Sep, 2015

PDB Images (7)

Image of CATH 5cf4

5cf4

PDB 5cf4

Image of CATH 5cf4A

5cf4A

PDB Chain 5cf4A

Image of CATH 5cf4B

5cf4B

PDB Chain 5cf4B

Image of CATH 5cf4A01

5cf4A01

CATH Domain 5cf4A01

Image of CATH 5cf4A02

5cf4A02

CATH Domain 5cf4A02

Image of CATH 5cf4B01

5cf4B01

CATH Domain 5cf4B01

Image of CATH 5cf4B02

5cf4B02

CATH Domain 5cf4B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	07 Sep, 2015	Chopped
B	07 Sep, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5cf4A01	30 Sep, 2015	3.30.200.20	Assigned
5cf4A02	30 Sep, 2015	1.10.510.10	Assigned
5cf4B01	30 Sep, 2015	3.30.200.20	Assigned
5cf4B02	30 Sep, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2