PDB Information

PDB5CEH
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.
Vinogradova, M., Gehling, V.S., Gustafson, A., Arora, S., Tindell, C.A., Wilson, C., Williamson, K.E., Guler, G.D., Gangurde, P., Manieri, W., Busby, J., Flynn, E.M., Lan, F., Kim, H.J., Odate, S., Cochran, A.G., Liu, Y., Wongchenko, M., Yang, Y., Cheung, T.K., Maile, T.M., Lau, T., Costa, M., Hegde, G.V., Jackson, E., Pitti, R., Arnott, D., Bailey, C., Bellon, S., Cummings, R.T., Albrecht, B.K., Harmange, J.C., Kiefer, J.R., Trojer, P., Classon, M.
Nat.Chem.Biol.
HeaderOxidoreductase/Inhibitor
Released2015-07-06
Resolution3.140
CATH Insert Date29 May, 2016

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2016 Chopped
B 30 May, 2016 Rejected

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
5cehA01 23 Jan, 2017 2.60.120.650 Assigned
5cehA02 23 Jan, 2017 1.10.150.60 Assigned
5cehA03 23 Jan, 2017 Write scan list

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P29375 KDM5A_HUMAN Homo sapiens Lysine-specific demethylase 5A