PDB Information

PDB5C7B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP.
Chessari, G., Buck, I.M., Day, J.E., Day, P.J., Iqbal, A., Johnson, C.N., Lewis, E.J., Martins, V., Miller, D., Reader, M., Rees, D.C., Rich, S.J., Tamanini, E., Vitorino, M., Ward, G.A., Williams, P.A., Williams, G., Wilsher, N.E., Woolford, A.J.
J.Med.Chem.
HeaderApoptosis
Released2015-06-24
Resolution2.680
CATH Insert Date30 Aug, 2015

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 31 Aug, 2015 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5c7bA00 03 Sep, 2015 1.10.1170.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP