PDB 5c5r

PDB Information

PDB5C5R
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
de Vicente, J., Tivitmahaisoon, P., Berry, P., Bolin, D.R., Carvajal, D., He, W., Huang, K.S., Janson, C., Liang, L., Lukacs, C., Petersen, A., Qian, H., Yi, L., Zhuang, Y., Hermann, J.C.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-06-21
Resolution1.550
CATH Insert Date30 Aug, 2015

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 31 Aug, 2015 Chopped
B 31 Aug, 2015 Chopped
C 31 Aug, 2015 Chopped
D 31 Aug, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5c5rA00 03 Sep, 2015 3.90.228.10 Assigned
5c5rB00 03 Sep, 2015 3.90.228.10 Assigned
5c5rC00 03 Sep, 2015 6.20.320.10 Assigned
5c5rD00 03 Sep, 2015 6.20.320.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2