PDB 5axq

PDB Links
Overview

PDB Information

PDB	5AXQ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design and synthesis of a novel 2-oxindole scaffold as a highly potent and brain-penetrant phosphodiesterase 10A inhibitor Yoshikawa, M., Kamisaki, H., Kunitomo, J., Oki, H., Kokubo, H., Suzuki, A., Ikemoto, T., Nakashima, K., Kamiguchi, N., Harada, A., Kimura, H., Taniguchi, T. Bioorg.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-07-31
Resolution	1.770
CATH Insert Date	29 Nov, 2015

PDB Images (5)

Image of CATH 5axq

5axq

PDB 5axq

Image of CATH 5axqA

5axqA

PDB Chain 5axqA

Image of CATH 5axqB

5axqB

PDB Chain 5axqB

Image of CATH 5axqA00

5axqA00

CATH Domain 5axqA00

Image of CATH 5axqB00

5axqB00

CATH Domain 5axqB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	30 Nov, 2015	Chopped
B	30 Nov, 2015	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5axqA00	02 Dec, 2015	1.10.1300.10	Assigned
5axqB00	03 Dec, 2015	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A