PDB Information

PDB5AVL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists
Matsui, Y., Yamaguchi, T., Yamazaki, T., Yoshida, M., Arai, M., Terasaka, N., Honzumi, S., Wakabayashi, K., Hayashi, S., Nakai, D., Hanzawa, H., Tamaki, K.
Bioorg.Med.Chem.Lett.
HeaderTranscription
Released2015-06-17
Resolution2.800
CATH Insert Date06 Sep, 2015

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Sep, 2015 Chopped
B 07 Sep, 2015 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5avlA00 20 Mar, 2016 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q13133 NR1H3_HUMAN Homo sapiens Oxysterols receptor LXR-alpha
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1