PDB 5aqr

PDB Information

PDB5AQR
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.
Sci Rep
HeaderChaperone
Released2015-09-22
Resolution1.910
CATH Insert Date16 Oct, 2016

PDB Images (22)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped
E 17 Oct, 2016 Chopped
F 17 Oct, 2016 Chopped

CATH Domains (15)

Domain ID Date inserted into CATH Superfamily CATH Status
5aqrA01 25 Oct, 2016 3.30.420.40 Assigned
5aqrA02 25 Oct, 2016 3.30.30.30 Assigned
5aqrA03 25 Oct, 2016 3.30.420.40 Assigned
5aqrA04 25 Oct, 2016 3.90.640.10 Assigned
5aqrB00 22 Oct, 2016 1.20.58.120 Assigned
5aqrC01 25 Oct, 2016 3.30.420.40 Assigned
5aqrC02 25 Oct, 2016 3.30.30.30 Assigned
5aqrC03 25 Oct, 2016 3.30.420.40 Assigned
5aqrC04 25 Oct, 2016 3.90.640.10 Assigned
5aqrD00 22 Oct, 2016 1.20.58.120 Assigned
5aqrE01 25 Oct, 2016 3.30.420.40 Assigned
5aqrE02 25 Oct, 2016 3.30.30.30 Assigned
5aqrE03 25 Oct, 2016 3.30.420.40 Assigned
5aqrE04 25 Oct, 2016 3.90.640.10 Assigned
5aqrF00 22 Oct, 2016 1.20.58.120 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1