PDB 5aqg

PDB Information

PDB5AQG
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.
Sci Rep
HeaderChaperone
Released2015-09-22
Resolution2.240
CATH Insert Date06 Nov, 2016

PDB Images (22)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2016 Chopped
B 07 Nov, 2016 Chopped
C 07 Nov, 2016 Chopped
D 07 Nov, 2016 Chopped
E 07 Nov, 2016 Chopped
F 07 Nov, 2016 Chopped

CATH Domains (15)

Domain ID Date inserted into CATH Superfamily CATH Status
5aqgA01 10 Nov, 2016 3.30.420.40 Assigned
5aqgA02 10 Nov, 2016 3.30.30.30 Assigned
5aqgA03 10 Nov, 2016 3.30.420.40 Assigned
5aqgA04 10 Nov, 2016 3.90.640.10 Assigned
5aqgB00 10 Nov, 2016 1.20.58.120 Assigned
5aqgC01 10 Nov, 2016 3.30.420.40 Assigned
5aqgC02 10 Nov, 2016 3.30.30.30 Assigned
5aqgC03 10 Nov, 2016 3.30.420.40 Assigned
5aqgC04 10 Nov, 2016 3.90.640.10 Assigned
5aqgD00 10 Nov, 2016 1.20.58.120 Assigned
5aqgE01 09 Nov, 2016 3.30.420.40 Assigned
5aqgE02 09 Nov, 2016 3.30.30.30 Assigned
5aqgE03 09 Nov, 2016 3.30.420.40 Assigned
5aqgE04 09 Nov, 2016 3.90.640.10 Assigned
5aqgF00 09 Nov, 2016 1.20.58.120 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1