PDB 5aph

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PDB Links
Overview

PDB Information

PDB	5APH
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma. Olsson, R.I., Xue, Y., von Berg, S., Aagaard, A., McPheat, J., Hansson, E.L., Bernstrom, J., Hansson, P., Jirholt, J., Grindebacke, H., Leffler, A., Chen, R., Xiong, Y., Ge, H., Hansson, T.G., Narjes, F. ChemMedChem
Header	Transcription
Released	2015-09-16
Resolution	1.540
CATH Insert Date	06 Dec, 2015

PDB Images (4)

Image of CATH 5aph

5aph

PDB 5aph

Image of CATH 5aphA

5aphA

PDB Chain 5aphA

Image of CATH 5aphC

5aphC

PDB Chain 5aphC

Image of CATH 5aphA00

5aphA00

CATH Domain 5aphA00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	07 Dec, 2015	Chopped
C	07 Dec, 2015	Rejected

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5aphA00	05 Jan, 2016	1.10.565.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P51449	RORG_HUMAN	Homo sapiens	Nuclear receptor ROR-gamma
Q15596	NCOA2_HUMAN	Homo sapiens	Nuclear receptor coactivator 2