PDB Information

PDB5AJR
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA CRUZI
Primary Citation
Clinical Candidate Vt-1161'S Antiparasitic Effect in Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme Cyp51 from Trypanosoma Cruzi.
Hoekstra, W.J., Hargrove, T.Y., Wawrzak, Z., Da Gama Jaen Batista, D., Da Silva, C.F., Nefertiti, A.S.G., Rachakonda, G., Schotzinger, R.J., Villalta, F., Soeiro, M.D.N.C., Lepesheva, G.I.
Antimicrob.Agents Chemother.
HeaderOxidoreductase
Released2015-02-26
Resolution2.750
CATH Insert Date20 Dec, 2015

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Dec, 2015 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5ajrA00 05 Jan, 2016 1.10.630.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q7Z1V1 CP51_TRYCC Trypanosoma cruzi strain CL Brener Sterol 14-alpha demethylase