PDB 5ae8

PDB Links
Overview

PDB Information

PDB	5AE8
Method	X-RAY DIFFRACTION
Host Organism	SPODOPTERA FRUGIPERDA
Gene Source	MUS MUSCULUS
Primary Citation	Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase Gamma for the Treatment of Respiratory Disease. Down, K., Amour, A., Baldwin, I.R., Cooper, A.W.J., Deakin, A.M., Felton, L.M., Guntrip, S.B., Hardy, C., Harrison, Z.A., Jones, K.L., Jones, P., Keeling, S.E., Le, J., Livia, S., Lucas, F., Lunniss, C.J., Parr, N.J., Robinson, E., Rowland, P., Smith, S., Thomas, D.A., Vitulli, G., Washio, Y., Hamblin, J.N. J.Med.Chem.
Header	Transferase
Released	2015-08-26
Resolution	2.420
CATH Insert Date	27 Sep, 2015

PDB Images (7)

Image of CATH 5ae8

5ae8

PDB 5ae8

Image of CATH 5ae8A

5ae8A

PDB Chain 5ae8A

Image of CATH 5ae8A01

5ae8A01

CATH Domain 5ae8A01

Image of CATH 5ae8A02

5ae8A02

CATH Domain 5ae8A02

Image of CATH 5ae8A03

5ae8A03

CATH Domain 5ae8A03

Image of CATH 5ae8A04

5ae8A04

CATH Domain 5ae8A04

Image of CATH 5ae8A05

5ae8A05

CATH Domain 5ae8A05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	28 Sep, 2015	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5ae8A01	12 Jul, 2018	1.25.40.70	Assigned
5ae8A02	12 Jul, 2018	3.10.20.90	Assigned
5ae8A03	12 Jul, 2018	2.60.40.150	Assigned
5ae8A04	12 Jul, 2018	3.30.1010.10	Assigned
5ae8A05	12 Jul, 2018	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
O35904	PK3CD_MOUSE	Mus musculus	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform