PDB 4zzj

PDB Information

PDB4ZZJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.
Dai, H., Case, A.W., Riera, T.V., Considine, T., Lee, J.E., Hamuro, Y., Zhao, H., Jiang, Y., Sweitzer, S.M., Pietrak, B., Schwartz, B., Blum, C.A., Disch, J.S., Caldwell, R., Szczepankiewicz, B., Oalmann, C., Yee Ng, P., White, B.H., Casaubon, R., Narayan, R., Koppetsch, K., Bourbonais, F., Wu, B., Wang, J., Qian, D., Jiang, F., Mao, C., Wang, M., Hu, E., Wu, J.C., Perni, R.B., Vlasuk, G.P., Ellis, J.L.
Nat Commun
HeaderHydrolase
Released2015-05-22
Resolution2.740
CATH Insert Date26 Jul, 2015

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 27 Jul, 2015 Chopped
B 27 Jul, 2015 Rejected

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4zzjA01 09 Jan, 2018 Holding pen
4zzjA02 09 Jan, 2018 3.40.50.1220 Assigned
4zzjA03 09 Jan, 2018 3.30.1600.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04637 P53_HUMAN Homo sapiens Cellular tumor antigen p53
Q96EB6 SIR1_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-1