PDB 4zvz

PDB Information

PDB4ZVZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.
Chattopadhyay, D., Swingle, M.R., Salter, E.A., Wood, E., D'Arcy, B., Zivanov, C., Abney, K., Musiyenko, A., Rusin, S.F., Kettenbach, A., Yet, L., Schroeder, C.E., Golden, J.E., Dunham, W.H., Gingras, A.C., Banerjee, S., Forbes, D., Wierzbicki, A., Honkanen, R.E.
Biochem. Pharmacol.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-05-19
Resolution2.000
CATH Insert Date08 May, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 09 May, 2016 Chopped
B 09 May, 2016 Chopped
C 09 May, 2016 Chopped
D 09 May, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4zvzA00 22 Nov, 2016 3.60.21.10 Assigned
4zvzB00 22 Nov, 2016 3.60.21.10 Assigned
4zvzC00 22 Nov, 2016 3.60.21.10 Assigned
4zvzD00 22 Nov, 2016 3.60.21.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P53041 PPP5_HUMAN Homo sapiens Serine/threonine-protein phosphatase 5
P53041 PPP5_HUMAN Homo sapiens Serine/threonine-protein phosphatase 5
P53041 PPP5_HUMAN Homo sapiens Serine/threonine-protein phosphatase 5
P53041 PPP5_HUMAN Homo sapiens Serine/threonine-protein phosphatase 5