PDB 4zvz

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Overview

PDB Information

PDB	4ZVZ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C. Chattopadhyay, D., Swingle, M.R., Salter, E.A., Wood, E., D'Arcy, B., Zivanov, C., Abney, K., Musiyenko, A., Rusin, S.F., Kettenbach, A., Yet, L., Schroeder, C.E., Golden, J.E., Dunham, W.H., Gingras, A.C., Banerjee, S., Forbes, D., Wierzbicki, A., Honkanen, R.E. Biochem. Pharmacol.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-05-19
Resolution	2.000
CATH Insert Date	08 May, 2016

PDB Images (9)

Image of CATH 4zvz

4zvz

PDB 4zvz

Image of CATH 4zvzA

4zvzA

PDB Chain 4zvzA

Image of CATH 4zvzB

4zvzB

PDB Chain 4zvzB

Image of CATH 4zvzC

4zvzC

PDB Chain 4zvzC

Image of CATH 4zvzD

4zvzD

PDB Chain 4zvzD

Image of CATH 4zvzA00

4zvzA00

CATH Domain 4zvzA00

Image of CATH 4zvzB00

4zvzB00

CATH Domain 4zvzB00

Image of CATH 4zvzC00

4zvzC00

CATH Domain 4zvzC00

Image of CATH 4zvzD00

4zvzD00

CATH Domain 4zvzD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	09 May, 2016	Chopped
B	09 May, 2016	Chopped
C	09 May, 2016	Chopped
D	09 May, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zvzA00	22 Nov, 2016	3.60.21.10	Assigned
4zvzB00	22 Nov, 2016	3.60.21.10	Assigned
4zvzC00	22 Nov, 2016	3.60.21.10	Assigned
4zvzD00	22 Nov, 2016	3.60.21.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P53041	PPP5_HUMAN	Homo sapiens	Serine/threonine-protein phosphatase 5
P53041	PPP5_HUMAN	Homo sapiens	Serine/threonine-protein phosphatase 5
P53041	PPP5_HUMAN	Homo sapiens	Serine/threonine-protein phosphatase 5
P53041	PPP5_HUMAN	Homo sapiens	Serine/threonine-protein phosphatase 5