PDB 4ztf

PDB Links
Overview

PDB Information

PDB	4ZTF
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Human spumaretrovirus
Primary Citation	Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors. Raheem, I.T., Walji, A.M., Klein, D., Sanders, J.M., Powell, D.A., Abeywickrema, P., Barbe, G., Bennet, A., Clas, S.D., Dubost, D., Embrey, M., Grobler, J., Hafey, M.J., Hartingh, T.J., Hazuda, D.J., Miller, M.D., Moore, K.P., Pajkovic, N., Patel, S., Rada, V., Rearden, P., Schreier, J.D., Sisko, J., Steele, T.G., Truchon, J.F., Wai, J., Xu, M., Coleman, P.J. J.Med.Chem.
Header	Transferase/Dna/Inhibitor
Released	2015-05-14
Resolution	2.700
CATH Insert Date	18 Oct, 2015

PDB Images (10)

Image of CATH 4ztf

4ztf

PDB 4ztf

Image of CATH 4ztfA

4ztfA

PDB Chain 4ztfA

Image of CATH 4ztfB

4ztfB

PDB Chain 4ztfB

Image of CATH 4ztfC

4ztfC

PDB Chain 4ztfC

Image of CATH 4ztfD

4ztfD

PDB Chain 4ztfD

Image of CATH 4ztfA01

4ztfA01

CATH Domain 4ztfA01

Image of CATH 4ztfA02

4ztfA02

CATH Domain 4ztfA02

Image of CATH 4ztfA03

4ztfA03

CATH Domain 4ztfA03

Image of CATH 4ztfA04

4ztfA04

CATH Domain 4ztfA04

Image of CATH 4ztfB00

4ztfB00

CATH Domain 4ztfB00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	19 Oct, 2015	Chopped
B	19 Oct, 2015	Chopped
C	19 Oct, 2015	Rejected
D	19 Oct, 2015	Rejected

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ztfA01	31 Oct, 2015	1.10.340.70	Assigned
4ztfA02	31 Oct, 2015	2.30.30.140	Assigned
4ztfA03	31 Oct, 2015	3.30.420.10	Assigned
4ztfA04	31 Oct, 2015	6.10.20.110	Assigned
4ztfB00	01 Nov, 2015	3.30.420.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14350	POL_FOAMV	Human spumaretrovirus	Pro-Pol polyprotein
P14350	POL_FOAMV	Human spumaretrovirus	Pro-Pol polyprotein