PDB Information

PDB4Z22
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV.
Rasina, D., Otikovs, M., Leitans, J., Recacha, R., Borysov, O.V., Kanepe-Lapsa, I., Domraceva, I., Pantelejevs, T., Tars, K., Blackman, M.J., Jaudzems, K., Jirgensons, A.
J.Med.Chem.
HeaderHydrolase
Released2015-03-28
Resolution2.620
CATH Insert Date10 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4z22A01 02 May, 2016 2.40.70.10 Assigned
4z22A02 02 May, 2016 2.40.70.10 Assigned
4z22B01 02 May, 2016 2.40.70.10 Assigned
4z22B02 02 May, 2016 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P46925 PLM2_PLAFA Plasmodium falciparum Plasmepsin-2
P46925 PLM2_PLAFA Plasmodium falciparum Plasmepsin-2