PDB 4yzu

PDB Information

PDB4YZU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Rapid development of two factor IXa inhibitors from hit to lead.
Parker, D.L., Walsh, S., Li, B., Kim, E., Sharipour, A., Smith, C., Chen, Y.H., Berger, R., Harper, B., Zhang, T., Park, M., Shu, M., Wu, J., Xu, J., Dewnani, S., Sherer, E.C., Hruza, A., Reichert, P., Geissler, W., Sonatore, L., Ellsworth, K., Balkovec, J., Greenlee, W., Wood, H.B.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-03-25
Resolution1.410
CATH Insert Date28 Jun, 2015

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4yzuA01 27 Jul, 2015 2.40.10.10 Assigned
4yzuA02 27 Jul, 2015 2.40.10.10 Assigned
4yzuB00 27 Jul, 2015 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00740 FA9_HUMAN Homo sapiens Coagulation factor IX
P00740 FA9_HUMAN Homo sapiens Coagulation factor IX
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