PDB 4yps

PDB Information

PDB4YPS
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHomo sapiens
Primary Citation
(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Choi, H.S., Rucker, P.V., Wang, Z., Fan, Y., Albaugh, P., Chopiuk, G., Gessier, F., Sun, F., Adrian, F., Liu, G., Hood, T., Li, N., Jia, Y., Che, J., McCormack, S., Li, A., Li, J., Steffy, A., Culazzo, A., Tompkins, C., Phung, V., Kreusch, A., Lu, M., Hu, B., Chaudhary, A., Prashad, M., Tuntland, T., Liu, B., Harris, J., Seidel, H.M., Loren, J., Molteni, V.
Acs Med.Chem.Lett.
HeaderTransfease/Transferase Inhibitor
Released2015-03-13
Resolution2.100
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ypsA01 22 Jul, 2015 3.30.200.20 Assigned
4ypsA02 22 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P04629 NTRK1_HUMAN Homo sapiens High affinity nerve growth factor receptor
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