PDB 4y74

PDB Links
Overview

PDB Information

PDB	4Y74
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. Huber, E.M., de Bruin, G., Heinemeyer, W., Paniagua Soriano, G., Overkleeft, H.S., Groll, M. J.Am.Chem.Soc.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-02-13
Resolution	2.700
CATH Insert Date	28 Jun, 2015

PDB Images (63)

4y74

PDB 4y74

4y74a

PDB Chain 4y74a

4y74A

PDB Chain 4y74A

4y74b

PDB Chain 4y74b

4y74B

PDB Chain 4y74B

4y74c

PDB Chain 4y74c

4y74C

PDB Chain 4y74C

4y74d

PDB Chain 4y74d

4y74D

PDB Chain 4y74D

4y74e

PDB Chain 4y74e

4y74E

PDB Chain 4y74E

4y74f

PDB Chain 4y74f

4y74F

PDB Chain 4y74F

4y74g

PDB Chain 4y74g

4y74G

PDB Chain 4y74G

4y74h

PDB Chain 4y74h

4y74H

PDB Chain 4y74H

4y74I

PDB Chain 4y74I

4y74J

PDB Chain 4y74J

4y74K

PDB Chain 4y74K

4y74L

PDB Chain 4y74L

4y74M

PDB Chain 4y74M

4y74N

PDB Chain 4y74N

4y74O

PDB Chain 4y74O

4y74P

PDB Chain 4y74P

4y74Q

PDB Chain 4y74Q

4y74R

PDB Chain 4y74R

4y74S

PDB Chain 4y74S

4y74T

PDB Chain 4y74T

4y74U

PDB Chain 4y74U

4y74V

PDB Chain 4y74V

4y74W

PDB Chain 4y74W

4y74X

PDB Chain 4y74X

4y74Y

PDB Chain 4y74Y

4y74Z

PDB Chain 4y74Z

4y74a00

CATH Domain 4y74a00

4y74A00

CATH Domain 4y74A00

4y74b00

CATH Domain 4y74b00

4y74B00

CATH Domain 4y74B00

4y74C00

CATH Domain 4y74C00

4y74D00

CATH Domain 4y74D00

4y74E00

CATH Domain 4y74E00

4y74F00

CATH Domain 4y74F00

4y74G00

CATH Domain 4y74G00

4y74H00

CATH Domain 4y74H00

4y74I00

CATH Domain 4y74I00

4y74J00

CATH Domain 4y74J00

4y74K00

CATH Domain 4y74K00

4y74L00

CATH Domain 4y74L00

4y74M00

CATH Domain 4y74M00

4y74N00

CATH Domain 4y74N00

4y74O00

CATH Domain 4y74O00

4y74P00

CATH Domain 4y74P00

4y74Q00

CATH Domain 4y74Q00

4y74R00

CATH Domain 4y74R00

4y74S00

CATH Domain 4y74S00

4y74T00

CATH Domain 4y74T00

4y74U00

CATH Domain 4y74U00

4y74V00

CATH Domain 4y74V00

4y74W00

CATH Domain 4y74W00

4y74X00

CATH Domain 4y74X00

4y74Y00

CATH Domain 4y74Y00

4y74Z00

CATH Domain 4y74Z00

PDB Prints

PDB Chains (34)

Chain ID	Date inserted into CATH	CATH Status
a	29 Jun, 2015	Chopped
A	29 Jun, 2015	Chopped
b	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped
c	29 Jun, 2015	Rejected
C	29 Jun, 2015	Chopped
d	29 Jun, 2015	Rejected
D	29 Jun, 2015	Chopped
e	29 Jun, 2015	Rejected
E	29 Jun, 2015	Chopped
f	29 Jun, 2015	Rejected
F	29 Jun, 2015	Chopped
g	29 Jun, 2015	Rejected
G	29 Jun, 2015	Chopped
h	29 Jun, 2015	Rejected
H	29 Jun, 2015	Chopped
I	29 Jun, 2015	Chopped
J	29 Jun, 2015	Chopped
K	29 Jun, 2015	Chopped
L	29 Jun, 2015	Chopped
M	29 Jun, 2015	Chopped
N	29 Jun, 2015	Chopped
O	29 Jun, 2015	Chopped
P	29 Jun, 2015	Chopped
Q	29 Jun, 2015	Chopped
R	29 Jun, 2015	Chopped
S	29 Jun, 2015	Chopped
T	29 Jun, 2015	Chopped
U	29 Jun, 2015	Chopped
V	29 Jun, 2015	Chopped
W	29 Jun, 2015	Chopped
X	29 Jun, 2015	Chopped
Y	29 Jun, 2015	Chopped
Z	29 Jun, 2015	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4y74a00	22 Jul, 2015	3.60.20.10	Assigned
4y74A00	22 Jul, 2015	3.60.20.10	Assigned
4y74b00	22 Jul, 2015	3.60.20.10	Assigned
4y74B00	22 Jul, 2015	3.60.20.10	Assigned
4y74C00	22 Jul, 2015	3.60.20.10	Assigned
4y74D00	22 Jul, 2015	3.60.20.10	Assigned
4y74E00	22 Jul, 2015	3.60.20.10	Assigned
4y74F00	22 Jul, 2015	3.60.20.10	Assigned
4y74G00	22 Jul, 2015	3.60.20.10	Assigned
4y74H00	22 Jul, 2015	3.60.20.10	Assigned
4y74I00	22 Jul, 2015	3.60.20.10	Assigned
4y74J00	22 Jul, 2015	3.60.20.10	Assigned
4y74K00	22 Jul, 2015	3.60.20.10	Assigned
4y74L00	22 Jul, 2015	3.60.20.10	Assigned
4y74M00	22 Jul, 2015	3.60.20.10	Assigned
4y74N00	22 Jul, 2015	3.60.20.10	Assigned
4y74O00	22 Jul, 2015	3.60.20.10	Assigned
4y74P00	22 Jul, 2015	3.60.20.10	Assigned
4y74Q00	22 Jul, 2015	3.60.20.10	Assigned
4y74R00	22 Jul, 2015	3.60.20.10	Assigned
4y74S00	22 Jul, 2015	3.60.20.10	Assigned
4y74T00	22 Jul, 2015	3.60.20.10	Assigned
4y74U00	22 Jul, 2015	3.60.20.10	Assigned
4y74V00	22 Jul, 2015	3.60.20.10	Assigned
4y74W00	22 Jul, 2015	3.60.20.10	Assigned
4y74X00	22 Jul, 2015	3.60.20.10	Assigned
4y74Y00	22 Jul, 2015	3.60.20.10	Assigned
4y74Z00	22 Jul, 2015	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7