PDB Information

PDB4XT2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2.
Scheuermann, T.H., Stroud, D., Sleet, C.E., Bayeh, L., Shokri, C., Wang, H., Caldwell, C.G., Longgood, J., MacMillan, J.B., Bruick, R.K., Gardner, K.H., Tambar, U.K.
J.Med.Chem.
HeaderTranscription
Released2015-01-22
Resolution1.700
CATH Insert Date20 Dec, 2015

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 21 Dec, 2015 Chopped
B 21 Dec, 2015 Chopped
C 21 Dec, 2015 Chopped
D 21 Dec, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4xt2A00 12 Jan, 2017 3.30.450.20 Assigned
4xt2B01 12 Jan, 2017 3.30.450.20 Assigned
4xt2C00 12 Jan, 2017 3.30.450.20 Assigned
4xt2D01 12 Jan, 2017 3.30.450.20 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P27540 ARNT_HUMAN Homo sapiens Aryl hydrocarbon receptor nuclear translocator
P27540 ARNT_HUMAN Homo sapiens Aryl hydrocarbon receptor nuclear translocator
Q99814 EPAS1_HUMAN Homo sapiens Endothelial PAS domain-containing protein 1
Q99814 EPAS1_HUMAN Homo sapiens Endothelial PAS domain-containing protein 1