PDB 4wyo

PDB Information

PDB4WYO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceSaccharomyces cerevisiae
Primary Citation
Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes.
Griffith, D.A., Kung, D.W., Esler, W.P., Amor, P.A., Bagley, S.W., Beysen, C., Carvajal-Gonzalez, S., Doran, S.D., Limberakis, C., Mathiowetz, A.M., McPherson, K., Price, D.A., Ravussin, E., Sonnenberg, G.E., Southers, J.A., Sweet, L.J., Turner, S.M., Vajdos, F.F.
J.Med.Chem.
HeaderLigase/Ligase Inhibitor
Released2014-11-17
Resolution2.890
CATH Insert Date28 Jun, 2015

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4wyoB01 20 Dec, 2016 3.90.226.10 Assigned
4wyoB02 20 Dec, 2016 2.40.460.10 Assigned
4wyoB03 20 Dec, 2016 3.90.226.10 Assigned
4wyoC01 20 Dec, 2016 3.90.226.10 Assigned
4wyoC02 20 Dec, 2016 2.40.460.10 Assigned
4wyoC03 20 Dec, 2016 3.90.226.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q00955 ACAC_YEAST Saccharomyces cerevisiae S288C Acetyl-CoA carboxylase
Q00955 ACAC_YEAST Saccharomyces cerevisiae S288C Acetyl-CoA carboxylase