PDB 4wt2

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Overview

PDB Information

PDB	4WT2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic Acid Inhibitor of the MDM2-p53 Interaction. Rew, Y., Sun, D., Yan, X., Beck, H.P., Canon, J., Chen, A., Duquette, J., Eksterowicz, J., Fox, B.M., Fu, J., Gonzalez, A.Z., Houze, J., Huang, X., Jiang, M., Jin, L., Li, Y., Li, Z., Ling, Y., Lo, M.C., Long, A.M., McGee, L.R., McIntosh, J., Oliner, J.D., Osgood, T., Saiki, A.Y., Shaffer, P., Wang, Y.C., Wortman, S., Yakowec, P., Ye, Q., Yu, D., Zhao, X., Zhou, J., Medina, J.C., Olson, S.H. J.Med.Chem.
Header	Ligase/Ligase Inhibitor
Released	2014-10-30
Resolution	1.420
CATH Insert Date	21 Dec, 2014

PDB Images (3)

Image of CATH 4wt2

4wt2

PDB 4wt2

Image of CATH 4wt2A

4wt2A

PDB Chain 4wt2A

Image of CATH 4wt2A01

4wt2A01

CATH Domain 4wt2A01

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	22 Dec, 2014	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4wt2A01	28 Dec, 2014	1.10.245.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2