PDB Information

Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic Acid Inhibitor of the MDM2-p53 Interaction.
Rew, Y., Sun, D., Yan, X., Beck, H.P., Canon, J., Chen, A., Duquette, J., Eksterowicz, J., Fox, B.M., Fu, J., Gonzalez, A.Z., Houze, J., Huang, X., Jiang, M., Jin, L., Li, Y., Li, Z., Ling, Y., Lo, M.C., Long, A.M., McGee, L.R., McIntosh, J., Oliner, J.D., Osgood, T., Saiki, A.Y., Shaffer, P., Wang, Y.C., Wortman, S., Yakowec, P., Ye, Q., Yu, D., Zhao, X., Zhou, J., Medina, J.C., Olson, S.H.
HeaderLigase/Ligase Inhibitor
CATH Insert Date21 Dec, 2014

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4wt2A01 28 Dec, 2014 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2